Historical Overview of Synthetic Vascular Prostheses

Editorial: Overview and Challenges of Implantable Auditory Prostheses

Historical development of lower-extremity prostheses.

In studying the history of the construction of artificial limbs to sub­ stitute for lost legs, which has been transmitted to us by written words, objects of art and handicraft, objects found in excavations, and so forth, and learning of the development of the artificial leg through the centuries, one gains knowledge of the foundation on which modern prosthetics is based. Such an historical revi...

Historical overview of transplantation.

Except for legends and claims of miracles, most histories of transplantation cover only the last 60 years because there were no earlier successes. However, the story of even this era has been documented in such rich detail that a full account would fill several volumes. Thus, this brief summary must be limited to highly selected "landmarks." Some landmarks had an immediate impact, but the impor...

Paclitaxel-eluting biodegradable synthetic vascular prostheses: a step towards reduction of neointima formation?

BACKGROUND Clinical small-caliber vascular prostheses are unsatisfactory. Reasons for failure are early thrombosis and late intimal hyperplasia. We thus prepared biodegradable small-caliber vascular prostheses using electrospun polycaprolactone (PCL) with slow-releasing paclitaxel (PTX), an antiproliferative drug. METHODS AND RESULTS PCL solutions containing PTX were used to prepare nonwoven ...

editorial: overview and challenges of implantable auditory prostheses

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